Endocarditis infection commonly related to health care factors,
increasingly due to staph
June 21, 2005
Laptop Battery An international study reveals that infective endocarditis,
infection and inflammation involving the heart valves is commonly
associated with health care factors and is increasingly due to
staphylococcal infection, according to a study in the June 22/29
issue of JAMA.
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Thinkpad For decades, infective endocarditis (IE) caused by
Staphylococcus aureus has been viewed primarily as a
community-acquired disease, especially associated with injection
drug use, according to background information in the article.
Because no large, prospectively collected, and geographically
diverse cohort of patients with IE existed before now, the global
significance and impact of regional variations on the
characteristics, treatment, and outcome of S aureus IE has not been
known.
acquired and health care–related infections are an increasing threat to patient safety and health in the United States (Weinstein RA 1991; Weinstein RA 1998). In the United States, infections encountered in the hospital or a health care facility affect more than 2 million patients, cost $4.5 billion, and contribute to 88, 000 deaths in hospitals annually (Malone DL et al 2002; Tasota FJ et al 1998).
Microsoft Vance G. Fowler, Jr., M.D., M.H.S., of Duke University Medical
Center, Durham, N.C., and colleagues conducted a study to document
the characteristics of IE caused by S aureus, including IE
associated with health care contact and IE due to
methicillin-resistant S aureus (MRSA), in different parts of the
world; and assessed regional differences and the effect of these
differences on clinical outcomes among patients with S aureus IE.
The study included 1,779 patients with IE from 39 medical centers
in 16 countries. The patients were enrolled in the International
Collaboration on Endocarditis-Prospective Cohort Study from June
2000 to December 2003.
Tea tree preparations may be as effective as drug therapy for the treatment of certain staph skin infections…
Laptop Computers The researchers found that S aureus was the most common pathogen
among the 1779 cases (558 patients, 31.4 percent). Health
care-associated infection was the most common form of S aureus IE
(218 patients, 39.1 percent), accounting for 25.9 percent
(Australia/New Zealand) to 54.2 percent (Brazil) of cases. Most
patients with health care-associated S aureus IE (131 patients,
60.1 percent) acquired the infection outside of the hospital. MRSA
IE was more common in the United States (37.2 percent) and Brazil
(37.5 percent) than in Europe/Middle East (23.7 percent) and
Australia/New Zealand (15.5 percent). Patients in the United States
were most likely to be hemodialysis dependent, to have diabetes, to
have a presumed intravascular device source, to receive vancomycin,
to be infected with MRSA, and to have persistent bacteremia.
The signs can range from raised circular lesions to generalized flakiness and hair loss. Intense itching usually accompanies the condition. Staph allergies can also be secondary to some primary allergic condition. For example a dog that has a flea infestation will initially itch due to the allergic reaction from the fleas, then develop a Staph infection and itch from the bacterial infection as well as the flea infestation.
Laptop Computer "The finding of S aureus as the leading cause of IE differs from
previous reports and may be due in part to increasing rates of
staphylococcal bacteremia related to health care contact in
industrialized nations," the authors write.
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Desktop Computer "S aureus is now the most common cause of IE in many areas of
the developed world. Patients with IE due to S aureus exhibit
distinct characteristics compared with patients with IE due to
other pathogens. Health care�associated IE is emerging as the
most common form of S aureus IE and has distinct features compared
with more familiar forms of S aureus IE, such as community-acquired
injection drug use-associated infection. MRSA is now encountered
internationally as a relatively common cause of IE and is
associated with persistent bacteremia. Future investigations are
required to identify better treatment and prevention strategies for
this serious and common consequence of medical progress," the
authors conclude.
Notebooks JAMA and Archives Journals
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