Flu institute a booster shot for Wisconsin biotech stature
Laptop Battery By Joe Vanden Plas • 03/15/06
Wisconsins reputation as a biotechnology leader was greatly
enhanced today with the announcement that an Institute for
Influenza Viral Research will be established by UW-Madison.
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Thinkpad Thats the assessment of Mark Bugher, director of University
Research Park, where the research institute will be located. Bugher
said the institute, which is designed to accelerate the pace of
research into the most basic properties of the flu virus, and help
prepare for a possible pandemic caused by the avian flu, might have
the same impact on the states image as stem cell research.
Microsoft Alex Azar II, deputy secretary of the U.S. Department of
Health and Human Services, was
in Madison for the announcement. Azar said a vaccine exists with
some effectiveness against avian flu in humans, but production
is slow because the nation has neglected immunization
infrastructure. He estimated the U.S. could produce 14 million
doses of avian flu vaccine a year but only if the production of
vaccines for normal, seasonal flu were suspended, leading to an
unknown number of deaths.
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Laptop Computers Azar said the federal
government is distributing $100
million to the states for pandemic preparedness, of which
Wisconsin is getting $1.8 million. States will receive a further
$250 million later this year.
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Laptop Computer The new research center is being funded separately, with $6
million coming from the Wisconsin Alumni Research Foundation and a
further $3 million from federal grants.
laptop computers is driving strong sales for notebook computers, according to the latest quarterly sales figures from the research firm IDC, which reported a 37% computer sales for the second quarter, compared with a year earlier. In the U.S., laptop sales grew 17.7%, while sales of desktop computers and servers fell 4%. The New York Times ( 10), CNET ( 10)
Desktop Computer More on WTN: IT critical in pandemic response, but many are not
paying attention
Notebooks KawaokaUW-Madison professor of virology Yoshihiro Kawaoka will
direct the 20,000-square-foot institute, which will be housed in a
remodeled building. His research into flu virus mutations has been
lauded by the World Health Organization as one of the worlds
pre-eminent influenza projects.
Lenovo Kawaoka was out of the country and unavailable for comment, but
Bugher said the avian flu vaccine is up there with stem cells in
terms of breakthrough technology. The avian flu is being talked
about almost every day in the international news, noted Bugher, who
is working to develop a second University Research Park campus on
Madisons Far West side. If Wisconsin can become the centerpiece for
avian flu research, and scientist Yoshi Kawaoka is certainly an
acknowledged worldwide leader in that effort, I think its a big
deal.
Hard Drive Several of Kawaokas discoveries on vaccine development have been
patented by the Wisconsin Alumni Research Foundation, which is
partially funding the institute. His technology will be refined in
larger, more specialized laboratory space, and UW-Madison plans to
add three new faculty positions in the area of viral vaccine
research. Up to 28 people would be employed at the institute.
Travelstar News of the institute, which should open by the fall of 2007,
also makes it more likely that the state will hang on to the highly
regarded Kawaoka, which Bugher acknowledged is part of the
strategy.
Gateway James Tracy, associate dean for research at the UW-Madison
School of Veterinary Medicine, sees an additional benefit in
commercial spin-offs. The technology that Yoshi has devised will
facilitate the production of new vaccines, Tracy said, and his
basic research could facilitate the discovery of new drugs of the
ilk of Tamiflu.
Laptop Parts Kawaoka is among a group of researchers that reported the
existence of a Vietnamese girl with a strain of the H5N1 avian flu
virus that is resistant to Tamiflu. As a result, the sole reliance
on the drug, which is being stockpiled around the globe, has been
called into question.
Software One of the challenges with influenza-A viruses is they mutate as
they go through different organisms, either of the same species or
when they jump species, which increases the degree of difficulty of
making new flu vaccines. The work of Kawaokas research group in the
area of reverse genetics has enabled drug manufacturers to more
quickly produce vaccines for new strains, and identify new
molecular targets for anti-viral drugs. According to UW-Madison, a
more recent discovery indicates how flu viruses organize their
genetic material to create infectious particles.
Hard Drives Kawaokas lab is studying the molecular basis of the high
virulence of the H5N1 avian flu virus in mammals, and how it was
directly transmitted from birds to humans. His research is
basically on the virus, itself, how it causes pathogenicity, and
how it enters cells, and that provides the clues to the technology
on how to make vaccines and drugs, Tracy said.
Electronics Want to hear more about pandemic flu, and how technology will
be called on to help deal with it? It's one topic of the Digital
Healthcare Conference in Madison on May 3-4. Visit the site
now.
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